Australian Institute of Physics |
|
South Australian Branch |
2008 Student Night
presented by the
Australian Institute of Physics
(SA branch)
http://www.physics.adelaide.edu.au/aip-sa
aip-sa@physics.adelaide.edu.au
Ph: (08) 8201 2093 or (08) 8277 7036 (a.h.) Fax: (08) 8201 2905
Post: AIP-SA secretary, c/o SoCPES, Flinders University, GPO Box 2100, Adelaide SA 5001
at
8:00 pm on Thursday 14th August 2008 inKerr Grant Lecture Theatre , Physics Building
Note. Security restrictions require that entry to the building is supervised. It is therefore essential that attendees arrive before 8:00pm. Entry will not be possible after this time.
Postgraduate Physics students from South Australian Universities will talk
about their research work:
Radiation therapy (RT) is a form of cancer treatment, which uses ionising radiation to kill tumour cells through DNA damage. There are many tumour properties that can vary from patient to patient, with many tumours e.g. head and neck cancers, exhibiting low oxygen levels (hypoxia), affecting the ability of radiation to damage DNA. It is the aim of many clinicians to individualise RT to improve patient outcomes by tailoring the treatment planning to specific tumour parameters, including the hypoxic cell percentage, as well as many other factors.
A model is in development to simulate cell division, using data such as: cell cycle times, stem cell percentages, and cellular oxygenation. Oxygen levels may be measured in tumours using a fibre optic probe which allows data from real tumour systems (e.g. genetically altered mice) to be input into the model. A RT module is in development to simulate different radiation schedules, as well as effects such as reoxygenation and accelerated cell repopulation which occur during treatment. This will allow for more specific RT planning, through predictions of cell kill for the individual patient.
"TWO BODY CALCULATIONS WITH THE GAUGING OF EQUATIONS METHOD"